NORPLANT vs PROVERA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. NORPLANT and PROVERA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NORPLANT	PROVERA
Rating	New	64/100
Pharmacy pays	~$192.31 /30	~$562.79 /30
Type	RX	RX
Active ingredient	LEVONORGESTREL	MEDROXYPROGESTERONE ACETATE
Manufacturer	Population Council	Pfizer
Dosage forms	Implant	Tablet
Drug class	Progestin	Progestin
Boxed warning	None	Boxed warning
Half-life	about 36 hours (36 ± 13 hours at steady state)	—
Treats	—	Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

norplant provera

Rating

New

64/100

Pharmacy pays

~$192.31 /30

~$562.79 /30

Type

Active ingredient

LEVONORGESTREL

MEDROXYPROGESTERONE ACETATE

Manufacturer

Population Council

Pfizer

Dosage forms

Implant

Tablet

Drug class

Progestin

Boxed warning

None

Boxed warning

Half-life

about 36 hours (36 ± 13 hours at steady state)

—

Treats

—

Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

Frequently asked questions

Which is cheaper, Norplant or Provera?

Norplant costs pharmacies less to acquire — about $192.31 vs $562.79 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Norplant and Provera?

Norplant contains Levonorgestrel, while Provera contains Medroxyprogesterone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.