NORLESTRIN FE 1/50 vs RETIN-A

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. NORLESTRIN FE 1/50 and RETIN-A are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NORLESTRIN FE 1/50	RETIN-A
Rating	New	74/100
Pharmacy pays	—	$1.05 /g
Type	RX	RX
Active ingredient	ETHINYL ESTRADIOL AND FERROUS FUMARATE AND NORETHINDRONE ACETATE	TRETINOIN
Manufacturer	Parke Davis	Valeant Pharm Intl
Dosage forms	Tablet	Topical
Drug class	—	Retinoid
Boxed warning	None	None
Half-life	about 8 hours	—
Treats	—	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

norlestrin fe 1/50 retin-a

Rating

New

74/100

Pharmacy pays

—

$1.05 /g

Type

Active ingredient

ETHINYL ESTRADIOL AND FERROUS FUMARATE AND NORETHINDRONE ACETATE

TRETINOIN

Manufacturer

Parke Davis

Valeant Pharm Intl

Dosage forms

Tablet

Topical

Drug class

—

Retinoid

Boxed warning

None

Half-life

about 8 hours

—

Treats

—

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

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Frequently asked questions

What is the difference between Norlestrin Fe 1/50 and Retin-A?

Norlestrin Fe 1/50 contains Ethinyl Estradiol and Ferrous Fumarate and Norethindrone Acetate, while Retin-A contains Tretinoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.