NIZORAL vs SPORANOX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 14, 2026·How we rate

Possible drug interaction. NIZORAL and SPORANOX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NIZORAL	SPORANOX
Rating	70/100	70/100
Pharmacy pays	$0.27 /g	$0.84 /mL
Type	RX	RX
Active ingredient	KETOCONAZOLE	ITRACONAZOLE
Manufacturer	Janssen Pharms	Janssen Pharms
Dosage forms	Topical	Capsule
Drug class	Azole Antifungal	Azole Antifungal
Boxed warning	None	None
Half-life	—	Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.
Treats	Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis	Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

nizoral sporanox

Rating

70/100

Pharmacy pays

$0.27 /g

$0.84 /mL

Type

Active ingredient

KETOCONAZOLE

ITRACONAZOLE

Manufacturer

Janssen Pharms

Dosage forms

Topical

Capsule

Drug class

Azole Antifungal

Boxed warning

None

Half-life

—

Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis

Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

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Frequently asked questions

Which is better-rated, Nizoral or Sporanox?

Nizoral and Sporanox are tied at 3.5 out of 5 by our independent rating.

What is the difference between Nizoral and Sporanox?

Nizoral contains Ketoconazole, while Sporanox contains Itraconazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.