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NIZORAL vs SPECTAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. NIZORAL and SPECTAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

nizoralspectazole

Rating

70/100
70/100

Pharmacy pays

$0.27 /g
$0.36 /g

Type

RX
RX

Active ingredient

KETOCONAZOLE
ECONAZOLE NITRATE

Manufacturer

Janssen Pharms
Alvogen

Dosage forms

Topical
Topical

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis
Cutaneous Candidiasis, Tinea Pedis, Tinea Versicolor

Get nizoralhigher-rated option

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Frequently asked questions

Which is better-rated, Nizoral or Spectazole?

Nizoral and Spectazole are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Nizoral or Spectazole?

Nizoral costs pharmacies less to acquire — about $0.27 vs $0.36 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Nizoral and Spectazole?

Nizoral contains Ketoconazole, while Spectazole contains Econazole Nitrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.