NIRAVAM vs VALRELEASE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. NIRAVAM and VALRELEASE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NIRAVAM	VALRELEASE
Rating	70/100	New
Pharmacy pays	~$0.76 /30	~$0.87 /30
Type	RX	RX
Active ingredient	ALPRAZOLAM	DIAZEPAM
Manufacturer	Ucb Inc	Roche
Dosage forms	Tablet, orally disintegrating	Capsule, extended release
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	None	None
Half-life	about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults	about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age
Treats	Agoraphobia, Depressive Disorder, Panic Disorder	Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

niravam valrelease

Rating

70/100

New

Pharmacy pays

~$0.76 /30

~$0.87 /30

Type

Active ingredient

ALPRAZOLAM

DIAZEPAM

Manufacturer

Ucb Inc

Roche

Dosage forms

Tablet, orally disintegrating

Capsule, extended release

Drug class

Benzodiazepine

Boxed warning

None

Half-life

about 11 hours (mean 11.2 hours; range roughly 6 to 27 hours) in healthy adults

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

Treats

Agoraphobia, Depressive Disorder, Panic Disorder

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

Frequently asked questions

Which is cheaper, Niravam or Valrelease?

Niravam costs pharmacies less to acquire — about $0.76 vs $0.87 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Niravam and Valrelease?

Niravam contains Alprazolam, while Valrelease contains Diazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.