NIACIN vs PLETAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. NIACIN and PLETAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NIACIN	PLETAL
Rating	New	New
Pharmacy pays	~$7.53 /30	~$3.80 /30
Type	RX	RX
Active ingredient	NIACIN	CILOSTAZOL
Manufacturer	Barr	Otsuka
Dosage forms	Tablet, Tablet, extended release	Tablet
Drug class	Nicotinic Acid	—
Boxed warning	None	None
Half-life	about 20 to 45 minutes	—
Treats	Hypercholesterolemia, Pellagra, Hypertriglyceridemia	Vascular Graft Occlusion, Intermittent Claudication, Peripheral Vascular Diseases

niacin pletal

Rating

New

Pharmacy pays

~$7.53 /30

~$3.80 /30

Type

Active ingredient

NIACIN

CILOSTAZOL

Manufacturer

Barr

Otsuka

Dosage forms

Tablet, Tablet, extended release

Tablet

Drug class

Nicotinic Acid

—

Boxed warning

None

Half-life

about 20 to 45 minutes

—

Treats

Hypercholesterolemia, Pellagra, Hypertriglyceridemia

Vascular Graft Occlusion, Intermittent Claudication, Peripheral Vascular Diseases

Frequently asked questions

Which is cheaper, Niacin or Pletal?

Pletal costs pharmacies less to acquire — about $3.80 vs $7.53 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Niacin and Pletal?

Niacin contains Niacin, while Pletal contains Cilostazol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.