Skip to content
ppharmaranks
Menu
CompaniesProductsDrug classesConditionsBest by conditionTreatmentsInteraction checkerFood & medicinesWhat pharmacies payPill identifierMedicines & breastfeedingChildren’s dosage chartsDo medicines expire?Crushing & splitting pillsHow long meds take to workAlternating Tylenol & ibuprofenDrug recallsSupplementsSafety & lawsuitsGuidesA–ZHow we rate

NEXIUM vs RANITIDINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. NEXIUM and RANITIDINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

nexiumranitidine hydrochloride

Rating

70/100
70/100

Pharmacy pays

—
—

Type

RX
RX

Active ingredient

ESOMEPRAZOLE MAGNESIUM
RANITIDINE HYDROCHLORIDE

Manufacturer

Astrazeneca
Wockhardt

Dosage forms

Capsule, delayed release, Powder, delayed release
Capsule

Drug class

Proton Pump Inhibitor
—

Boxed warning

None
None

Half-life

—
about 2.5 to 3 hours

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux
Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

Get nexiumhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is better-rated, Nexium or Ranitidine Hydrochloride?

Nexium and Ranitidine Hydrochloride are tied at 3.5 out of 5 by our independent rating.

What is the difference between Nexium and Ranitidine Hydrochloride?

Nexium contains Esomeprazole Magnesium, while Ranitidine Hydrochloride contains Ranitidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.