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NEXIUM vs NEXIUM 24HR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate
nexiumnexium 24hr

Rating

70/100
72/100

Pharmacy pays

—
—

Type

RX
OTC

Active ingredient

ESOMEPRAZOLE MAGNESIUM
ESOMEPRAZOLE MAGNESIUM

Manufacturer

Astrazeneca
Astrazeneca LP

Dosage forms

Capsule, delayed release, Powder, delayed release
Capsule, delayed release, Tablet

Drug class

Proton Pump Inhibitor
Proton Pump Inhibitor

Boxed warning

None
None

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux
Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Where to buy

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Frequently asked questions

Which is better-rated, Nexium or Nexium 24hr?

By our independent rating, Nexium 24hr scores higher — 3.6 vs 3.5 out of 5 for Nexium. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Nexium and Nexium 24hr?

Both Nexium and Nexium 24hr share the active ingredient Esomeprazole Magnesium, but Nexium is sold as RX and Nexium 24hr as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.