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NEXIUM 24HR vs PANTOPRAZOLE SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

70/100
New

Pharmacy pays

~$120.76 /30

Type

OTC
RX

Active ingredient

ESOMEPRAZOLE MAGNESIUM
PANTOPRAZOLE SODIUM

Dosage forms

Capsule, delayed release, Tablet
Powder, delayed release, Injectable, Solution, Powder, Tablet, delayed release

Drug class

Proton Pump Inhibitor
Proton Pump Inhibitor

Boxed warning

None
None

Half-life

about 1 hour

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux
Esophagitis, Gastroesophageal Reflux, Heartburn

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Nexium 24hr and Pantoprazole Sodium?

Nexium 24hr contains Esomeprazole Magnesium, while Pantoprazole Sodium contains Pantoprazole Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.