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ESOMEPRAZOLE MAGNESIUM vs NEXIUM 24HR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
esomeprazole magnesiumnexium 24hr

Rating

66/100
70/100

Pharmacy pays

—
—

Type

RX
OTC

Active ingredient

ESOMEPRAZOLE MAGNESIUM
ESOMEPRAZOLE MAGNESIUM

Manufacturer

Mylan
Astrazeneca LP

Dosage forms

Capsule, delayed release, Powder, extended release
Capsule, delayed release, Tablet

Drug class

Proton Pump Inhibitor
Proton Pump Inhibitor

Boxed warning

None
None

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux
Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

Get nexium 24hrhigher-rated option

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Frequently asked questions

Which is better-rated, Esomeprazole Magnesium or Nexium 24hr?

By our independent rating, Nexium 24hr scores higher — 3.5 vs 3.3 out of 5 for Esomeprazole Magnesium. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Esomeprazole Magnesium and Nexium 24hr?

Both Esomeprazole Magnesium and Nexium 24hr share the active ingredient Esomeprazole Magnesium, but Esomeprazole Magnesium is sold as RX and Nexium 24hr as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.