NEXICLON XR vs PRECEDEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. NEXICLON XR and PRECEDEX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NEXICLON XR	PRECEDEX
Rating	New	60/100
Pharmacy pays	~$1.05 /30	—
Type	RX	RX
Active ingredient	CLONIDINE	DEXMEDETOMIDINE HYDROCHLORIDE
Manufacturer	Rosemont	Hospira
Dosage forms	Tablet, extended release	Injectable
Drug class	Central Alpha-2 Adrenergic Agonist	Central Alpha-2 Adrenergic Agonist
Boxed warning	None	None
Half-life	about 12 to 16 hours	—
Treats	Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea	Pain, Psychomotor Agitation

nexiclon xr precedex

Rating

New

60/100

Pharmacy pays

~$1.05 /30

—

Type

Active ingredient

CLONIDINE

DEXMEDETOMIDINE HYDROCHLORIDE

Manufacturer

Rosemont

Hospira

Dosage forms

Tablet, extended release

Injectable

Drug class

Central Alpha-2 Adrenergic Agonist

Boxed warning

None

Half-life

about 12 to 16 hours

—

Treats

Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

Pain, Psychomotor Agitation

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Frequently asked questions

What is the difference between Nexiclon XR and Precedex?

Nexiclon XR contains Clonidine, while Precedex contains Dexmedetomidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.