NEUPRO vs REQUIP XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. NEUPRO and REQUIP XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NEUPRO	REQUIP XL
Rating	70/100	70/100
Pharmacy pays	—	~$2.41 /30
Type	RX	RX
Active ingredient	ROTIGOTINE	ROPINIROLE HYDROCHLORIDE
Manufacturer	Ucb Inc	Glaxosmithkline
Dosage forms	Patch, extended release, Kit	Tablet, extended release
Drug class	Nonergot Dopamine Agonist	Nonergot Dopamine Agonist
Boxed warning	None	None
Half-life	—	about 6 hours
Treats	Parkinson Disease, Restless Legs Syndrome	Parkinson Disease

neupro requip xl

Rating

70/100

Pharmacy pays

—

~$2.41 /30

Type

Active ingredient

ROTIGOTINE

ROPINIROLE HYDROCHLORIDE

Manufacturer

Ucb Inc

Glaxosmithkline

Dosage forms

Patch, extended release, Kit

Tablet, extended release

Drug class

Nonergot Dopamine Agonist

Boxed warning

None

Half-life

—

about 6 hours

Treats

Parkinson Disease, Restless Legs Syndrome

Parkinson Disease

Frequently asked questions

Which is better-rated, Neupro or Requip XL?

Neupro and Requip XL are tied at 3.5 out of 5 by our independent rating.

What is the difference between Neupro and Requip XL?

Neupro contains Rotigotine, while Requip XL contains Ropinirole Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.