NERLYNX vs SPRYCEL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. NERLYNX and SPRYCEL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NERLYNX	SPRYCEL
Rating	New	72/100
Pharmacy pays	—	~$839.19 /30
Type	RX	RX
Active ingredient	NERATINIB MALEATE	DASATINIB
Manufacturer	Puma Biotech	Bristol Myers Squibb
Dosage forms	Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Breast Neoplasms	Lymphoid Leukemia, Myeloid Leukemia

nerlynx sprycel

Rating

New

72/100

Pharmacy pays

—

~$839.19 /30

Type

Active ingredient

NERATINIB MALEATE

DASATINIB

Manufacturer

Puma Biotech

Bristol Myers Squibb

Dosage forms

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Breast Neoplasms

Lymphoid Leukemia, Myeloid Leukemia

Frequently asked questions

What is the difference between Nerlynx and Sprycel?

Nerlynx contains Neratinib Maleate, while Sprycel contains Dasatinib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.