NEREUS vs PROMETHAZINE PLAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. NEREUS and PROMETHAZINE PLAIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NEREUS	PROMETHAZINE PLAIN
Rating	New	New
Pharmacy pays	—	~$1.53 /30
Type	RX	RX
Active ingredient	TRADIPITANT	PROMETHAZINE HYDROCHLORIDE
Manufacturer	Vanda Pharms Inc	Pharmobedient
Dosage forms	Capsule	Syrup
Drug class	—	Phenothiazine
Boxed warning	None	Boxed warning
Half-life	—	about 9 to 16 hours
Treats	Motion Sickness	Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

nereus promethazine plain

Rating

New

Pharmacy pays

—

~$1.53 /30

Type

Active ingredient

TRADIPITANT

PROMETHAZINE HYDROCHLORIDE

Manufacturer

Vanda Pharms Inc

Pharmobedient

Dosage forms

Capsule

Syrup

Drug class

—

Phenothiazine

Boxed warning

None

Boxed warning

Half-life

—

about 9 to 16 hours

Treats

Motion Sickness

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Frequently asked questions

What is the difference between Nereus and Promethazine Plain?

Nereus contains Tradipitant, while Promethazine Plain contains Promethazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.