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NEORAL vs RESTASIS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

70/100
72/100

Pharmacy pays

~$52.85 /30
~$52.85 /30

Type

RX
RX

Active ingredient

CYCLOSPORINE
CYCLOSPORINE

Manufacturer

Dosage forms

Capsule, Solution
Emulsion

Drug class

Calcineurin Inhibitor Immunosuppressant
Calcineurin Inhibitor Immunosuppressant

Boxed warning

Half-life

about 8.4 hours (range 5 to 18 hours)
about 8.4 hours (range 5 to 18 hours)

Treats

Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus
Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

Frequently asked questions

Which is better-rated, Neoral or Restasis?

By our independent rating, Restasis scores higher — 3.6 vs 3.5 out of 5 for Neoral. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Neoral or Restasis?

Pharmacies pay about the same to acquire either one — roughly $52.85 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Neoral and Restasis?

Both Neoral and Restasis share the active ingredient Cyclosporine.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.