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NATESTO vs TESTODERM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

$0.65 /g
$0.65 /g

Type

RX
RX

Active ingredient

TESTOSTERONE
TESTOSTERONE

Manufacturer

Dosage forms

Topical, metered
Film, extended release

Drug class

Androgen
Androgen

Boxed warning

None
None

Half-life

about 10 to 100 minutes
about 10 to 100 minutes

Treats

Breast Neoplasms, Hypogonadism, Delayed Puberty
Breast Neoplasms, Hypogonadism, Delayed Puberty

Frequently asked questions

Which is cheaper, Natesto or Testoderm?

Pharmacies pay about the same to acquire either one — roughly $0.65 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Natesto and Testoderm?

Both Natesto and Testoderm share the active ingredient Testosterone.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.