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NARCAN vs VIVITROL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

New
70/100

Pharmacy pays

$4.41 /mL
~$36.35 /30

Type

OTC
RX

Active ingredient

NALOXONE HYDROCHLORIDE
NALTREXONE

Dosage forms

Spray/Inhaler
Kit

Drug class

Opioid Antagonist
Opioid Antagonist

Boxed warning

None
None

Half-life

30 to 81 minutes (mean 64 ± 12 minutes)

Treats

Opioid-Related Disorders, Respiration Disorders, Septic Shock
Alcoholism, Opioid-Related Disorders, Drug Overdose

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Narcan and Vivitrol?

Narcan contains Naloxone Hydrochloride, while Vivitrol contains Naltrexone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.