NARCAN vs REZENOPY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	NARCAN	REZENOPY
Rating	New	New
Pharmacy pays	$4.41 /mL	$4.41 /mL
Type	OTC	RX
Active ingredient	NALOXONE HYDROCHLORIDE	NALOXONE HYDROCHLORIDE
Manufacturer	Emergent	Scienture
Dosage forms	Spray/Inhaler	Spray/Inhaler
Drug class	Opioid Antagonist	Opioid Antagonist
Boxed warning	None	None
Half-life	30 to 81 minutes (mean 64 ± 12 minutes)	30 to 81 minutes (mean 64 ± 12 minutes)
Treats	Opioid-Related Disorders, Respiration Disorders, Septic Shock	Opioid-Related Disorders, Respiration Disorders, Septic Shock

narcan rezenopy

Rating

New

Pharmacy pays

$4.41 /mL

Type

OTC

Active ingredient

NALOXONE HYDROCHLORIDE

Manufacturer

Emergent

Scienture

Dosage forms

Spray/Inhaler

Drug class

Opioid Antagonist

Boxed warning

None

Half-life

30 to 81 minutes (mean 64 ± 12 minutes)

Treats

Opioid-Related Disorders, Respiration Disorders, Septic Shock

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Frequently asked questions

Which is cheaper, Narcan or Rezenopy?

Pharmacies pay about the same to acquire either one — roughly $4.41 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Narcan and Rezenopy?

Both Narcan and Rezenopy share the active ingredient Naloxone Hydrochloride, but Narcan is sold as OTC and Rezenopy as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.