NARCAN vs RELISTOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	NARCAN	RELISTOR
Rating	New	New
Pharmacy pays	$4.41 /mL	—
Type	OTC	RX
Active ingredient	NALOXONE HYDROCHLORIDE	METHYLNALTREXONE BROMIDE
Manufacturer	Emergent	Salix
Dosage forms	Spray/Inhaler	Injectable, Tablet
Drug class	Opioid Antagonist	Opioid Antagonist
Boxed warning	None	None
Half-life	30 to 81 minutes (mean 64 ± 12 minutes)	—
Treats	Opioid-Related Disorders, Respiration Disorders, Septic Shock	Constipation

narcan relistor

Rating

New

Pharmacy pays

$4.41 /mL

—

Type

OTC

Active ingredient

NALOXONE HYDROCHLORIDE

METHYLNALTREXONE BROMIDE

Manufacturer

Emergent

Salix

Dosage forms

Spray/Inhaler

Injectable, Tablet

Drug class

Opioid Antagonist

Boxed warning

None

Half-life

30 to 81 minutes (mean 64 ± 12 minutes)

—

Treats

Opioid-Related Disorders, Respiration Disorders, Septic Shock

Constipation

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Frequently asked questions

What is the difference between Narcan and Relistor?

Narcan contains Naloxone Hydrochloride, while Relistor contains Methylnaltrexone Bromide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.