NALOXONE vs NARCAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	NALOXONE	NARCAN
Rating	72/100	New
Pharmacy pays	$4.41 /mL	$4.41 /mL
Type	RX	OTC
Active ingredient	NALOXONE HYDROCHLORIDE	NALOXONE HYDROCHLORIDE
Manufacturer	Hikma	Emergent
Dosage forms	Injectable	Spray/Inhaler
Drug class	Opioid Antagonist	Opioid Antagonist
Boxed warning	None	None
Half-life	30 to 81 minutes (mean 64 ± 12 minutes)	30 to 81 minutes (mean 64 ± 12 minutes)
Treats	Opioid-Related Disorders, Respiration Disorders, Septic Shock	Opioid-Related Disorders, Respiration Disorders, Septic Shock

naloxone narcan

Rating

72/100

New

Pharmacy pays

$4.41 /mL

Type

OTC

Active ingredient

NALOXONE HYDROCHLORIDE

Manufacturer

Hikma

Emergent

Dosage forms

Injectable

Spray/Inhaler

Drug class

Opioid Antagonist

Boxed warning

None

Half-life

30 to 81 minutes (mean 64 ± 12 minutes)

Treats

Opioid-Related Disorders, Respiration Disorders, Septic Shock

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Frequently asked questions

Which is cheaper, Naloxone or Narcan?

Pharmacies pay about the same to acquire either one — roughly $4.41 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Naloxone and Narcan?

Both Naloxone and Narcan share the active ingredient Naloxone Hydrochloride, but Naloxone is sold as RX and Narcan as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.