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NAPROXEN vs VIOXX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. NAPROXEN and VIOXX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

naproxenvioxx

Rating

72/100
70/100

Pharmacy pays

$0.06 /mL
—

Type

RX
RX

Active ingredient

NAPROXEN
ROFECOXIB

Manufacturer

Hikma
Merck

Dosage forms

Tablet
Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
—

Boxed warning

Boxed warning
None

Half-life

about 12 to 17 hours
—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain
Dysmenorrhea, Osteoarthritis

Frequently asked questions

Which is better-rated, Naproxen or Vioxx?

By our independent rating, Naproxen scores higher — 3.6 vs 3.5 out of 5 for Vioxx. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Naproxen and Vioxx?

Naproxen contains Naproxen, while Vioxx contains Rofecoxib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.