NAPROXEN vs PIROXICAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. NAPROXEN and PIROXICAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NAPROXEN	PIROXICAM
Rating	72/100	72/100
Pharmacy pays	$0.06 /mL	~$5.35 /30
Type	RX	RX
Active ingredient	NAPROXEN	PIROXICAM
Manufacturer	Hikma	Unichem
Dosage forms	Tablet	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 12 to 17 hours	—
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Back Pain	Rheumatoid Arthritis, Inflammation, Osteoarthritis

naproxen piroxicam

Rating

72/100

Pharmacy pays

$0.06 /mL

~$5.35 /30

Type

Active ingredient

NAPROXEN

PIROXICAM

Manufacturer

Hikma

Unichem

Dosage forms

Tablet

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 12 to 17 hours

—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Frequently asked questions

Which is better-rated, Naproxen or Piroxicam?

Naproxen and Piroxicam are tied at 3.6 out of 5 by our independent rating.

What is the difference between Naproxen and Piroxicam?

Naproxen contains Naproxen, while Piroxicam contains Piroxicam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.