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NAPROXEN vs NAPROXEN SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Rating

72/100
New

Pharmacy pays

$0.06 /mL
$0.06 /mL

Type

RX
OTC

Active ingredient

NAPROXEN
NAPROXEN SODIUM

Dosage forms

Tablet
Capsule, Tablet, Tablet, extended release

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 12 to 17 hours
about 12 to 17 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain
Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

Get naproxen sodium

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is cheaper, Naproxen or Naproxen Sodium?

Pharmacies pay about the same to acquire either one — roughly $0.06 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Naproxen and Naproxen Sodium?

Naproxen contains Naproxen, while Naproxen Sodium contains Naproxen Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.