NALTREXONE vs NARCAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	NALTREXONE	NARCAN
Rating	56/100	New
Pharmacy pays	~$36.35 /30	$4.41 /mL
Type	RX	OTC
Active ingredient	NALTREXONE	NALOXONE HYDROCHLORIDE
Manufacturer	Teva	Emergent
Dosage forms	Kit	Spray/Inhaler
Drug class	Opioid Antagonist	Opioid Antagonist
Boxed warning	None	None
Half-life	—	30 to 81 minutes (mean 64 ± 12 minutes)
Treats	Alcoholism, Opioid-Related Disorders, Drug Overdose	Opioid-Related Disorders, Respiration Disorders, Septic Shock

naltrexone narcan

Rating

56/100

New

Pharmacy pays

~$36.35 /30

$4.41 /mL

Type

OTC

Active ingredient

NALTREXONE

NALOXONE HYDROCHLORIDE

Manufacturer

Teva

Emergent

Dosage forms

Kit

Spray/Inhaler

Drug class

Opioid Antagonist

Boxed warning

None

Half-life

—

30 to 81 minutes (mean 64 ± 12 minutes)

Treats

Alcoholism, Opioid-Related Disorders, Drug Overdose

Opioid-Related Disorders, Respiration Disorders, Septic Shock

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Frequently asked questions

What is the difference between Naltrexone and Narcan?

Naltrexone contains Naltrexone, while Narcan contains Naloxone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.