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NALFON vs RUFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. NALFON and RUFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$0.04 /mL

Type

RX
RX

Active ingredient

FENOPROFEN CALCIUM
IBUPROFEN

Manufacturer

Dosage forms

Capsule
Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

about 1.8 to 2.0 hours

Treats

Rheumatoid Arthritis, Osteoarthritis, Pain
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Frequently asked questions

What is the difference between Nalfon and Rufen?

Nalfon contains Fenoprofen Calcium, while Rufen contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.