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NAFCILLIN SODIUM vs PENICILLIN G POTASSIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. NAFCILLIN SODIUM and PENICILLIN G POTASSIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
56/100

Pharmacy pays

Type

RX
RX

Active ingredient

NAFCILLIN SODIUM
PENICILLIN G POTASSIUM

Manufacturer

Dosage forms

Injectable
Injectable, Solution

Drug class

Penicillin-Class Antibacterial
Penicillin-Class Antibacterial

Boxed warning

None
None

Treats

Cellulitis, Bacterial Endocarditis, Osteomyelitis
Actinomycosis, Anthrax, Botulism

Frequently asked questions

What is the difference between Nafcillin Sodium and Penicillin G Potassium?

Nafcillin Sodium contains Nafcillin Sodium, while Penicillin G Potassium contains Penicillin G Potassium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.