NABUMETONE vs NAPROXEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. NABUMETONE and NAPROXEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	NABUMETONE	NAPROXEN
Rating	68/100	72/100
Pharmacy pays	~$4.00 /30	$0.06 /mL
Type	RX	RX
Active ingredient	NABUMETONE	NAPROXEN
Manufacturer	Aurobindo Pharma Ltd	Hikma
Dosage forms	Tablet	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	—	about 12 to 17 hours
Treats	Rheumatoid Arthritis, Inflammation, Osteoarthritis	Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

nabumetone naproxen

Rating

68/100

72/100

Pharmacy pays

~$4.00 /30

$0.06 /mL

Type

Active ingredient

NABUMETONE

NAPROXEN

Manufacturer

Aurobindo Pharma Ltd

Hikma

Dosage forms

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

—

about 12 to 17 hours

Treats

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

Frequently asked questions

Which is better-rated, Nabumetone or Naproxen?

By our independent rating, Naproxen scores higher — 3.6 vs 3.4 out of 5 for Nabumetone. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Nabumetone and Naproxen?

Nabumetone contains Nabumetone, while Naproxen contains Naproxen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.