MYSOLINE vs XARTEMIS XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. MYSOLINE and XARTEMIS XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	XARTEMIS XR
Rating	74/100	72/100
Pharmacy pays	~$2.89 /30	$0.03 /mL
Type	RX	RX
Active ingredient	PRIMIDONE	ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Mallinckrodt
Dosage forms	Tablet	Tablet, extended release
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Half-life	—	about 3.5 to 4 hours
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline xartemis xr

Rating

74/100

72/100

Pharmacy pays

~$2.89 /30

$0.03 /mL

Type

Active ingredient

PRIMIDONE

ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Mallinckrodt

Dosage forms

Tablet

Tablet, extended release

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Half-life

—

about 3.5 to 4 hours

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

Which is better-rated, Mysoline or Xartemis XR?

By our independent rating, Mysoline scores higher — 3.7 vs 3.6 out of 5 for Xartemis XR. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Mysoline and Xartemis XR?

Mysoline contains Primidone, while Xartemis XR contains Acetaminophen and Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.