MYSOLINE vs ULTRACET

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. MYSOLINE and ULTRACET are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	ULTRACET
Rating	74/100	72/100
Pharmacy pays	~$2.89 /30	$0.03 /mL
Type	RX	RX
Active ingredient	PRIMIDONE	ACETAMINOPHEN AND TRAMADOL HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Janssen Pharms
Dosage forms	Tablet	Tablet
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Half-life	—	about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline ultracet

Rating

74/100

72/100

Pharmacy pays

~$2.89 /30

$0.03 /mL

Type

Active ingredient

PRIMIDONE

ACETAMINOPHEN AND TRAMADOL HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Janssen Pharms

Dosage forms

Tablet

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Half-life

—

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

Which is better-rated, Mysoline or Ultracet?

By our independent rating, Mysoline scores higher — 3.7 vs 3.6 out of 5 for Ultracet. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Mysoline and Ultracet?

Mysoline contains Primidone, while Ultracet contains Acetaminophen and Tramadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.