MYSOLINE vs TRI-LUMA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. MYSOLINE and TRI-LUMA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	TRI-LUMA
Rating	74/100	New
Pharmacy pays	~$2.89 /30	—
Type	RX	RX
Active ingredient	PRIMIDONE	FLUOCINOLONE ACETONIDE AND HYDROQUINONE AND TRETINOIN
Manufacturer	Valeant Pharm Intl	Galderma Labs LP
Dosage forms	Tablet	Topical
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline tri-luma

Rating

74/100

New

Pharmacy pays

~$2.89 /30

—

Type

Active ingredient

PRIMIDONE

FLUOCINOLONE ACETONIDE AND HYDROQUINONE AND TRETINOIN

Manufacturer

Valeant Pharm Intl

Galderma Labs LP

Dosage forms

Tablet

Topical

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

What is the difference between Mysoline and Tri-Luma?

Mysoline contains Primidone, while Tri-Luma contains Fluocinolone Acetonide and Hydroquinone and Tretinoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.