MYSOLINE vs TREXIMET

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. MYSOLINE and TREXIMET are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	TREXIMET
Rating	74/100	New
Pharmacy pays	~$2.89 /30	$0.06 /mL
Type	RX	RX
Active ingredient	PRIMIDONE	NAPROXEN SODIUM AND SUMATRIPTAN SUCCINATE
Manufacturer	Valeant Pharm Intl	Currax
Dosage forms	Tablet	Tablet
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	Boxed warning
Half-life	—	about 2 hours (terminal elimination half-life 115 ± 19 minutes)
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline treximet

Rating

74/100

New

Pharmacy pays

~$2.89 /30

$0.06 /mL

Type

Active ingredient

PRIMIDONE

NAPROXEN SODIUM AND SUMATRIPTAN SUCCINATE

Manufacturer

Valeant Pharm Intl

Currax

Dosage forms

Tablet

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Boxed warning

Half-life

—

about 2 hours (terminal elimination half-life 115 ± 19 minutes)

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

What is the difference between Mysoline and Treximet?

Mysoline contains Primidone, while Treximet contains Naproxen Sodium and Sumatriptan Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.