MYSOLINE vs TALWIN NX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. MYSOLINE and TALWIN NX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	TALWIN NX
Rating	74/100	70/100
Pharmacy pays	~$2.89 /30	$4.38 /mL
Type	RX	RX
Active ingredient	PRIMIDONE	NALOXONE HYDROCHLORIDE AND PENTAZOCINE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Sanofi Aventis US
Dosage forms	Tablet	Tablet
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Half-life	—	30 to 81 minutes (mean 64 ± 12 minutes)
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline talwin nx

Rating

74/100

70/100

Pharmacy pays

~$2.89 /30

$4.38 /mL

Type

Active ingredient

PRIMIDONE

NALOXONE HYDROCHLORIDE AND PENTAZOCINE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Sanofi Aventis US

Dosage forms

Tablet

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Half-life

—

30 to 81 minutes (mean 64 ± 12 minutes)

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

Which is better-rated, Mysoline or Talwin Nx?

By our independent rating, Mysoline scores higher — 3.7 vs 3.5 out of 5 for Talwin Nx. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Mysoline and Talwin Nx?

Mysoline contains Primidone, while Talwin Nx contains Naloxone Hydrochloride and Pentazocine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.