MYSOLINE vs PREMPRO (PREMARIN;CYCRIN)

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. MYSOLINE and PREMPRO (PREMARIN;CYCRIN) are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	PREMPRO (PREMARIN;CYCRIN)
Rating	74/100	New
Pharmacy pays	~$2.89 /30	—
Type	RX	RX
Active ingredient	PRIMIDONE	ESTROGENS, CONJUGATED AND MEDROXYPROGESTERONE ACETATE
Manufacturer	Valeant Pharm Intl	Wyeth Pharms Inc
Dosage forms	Tablet	Tablet
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline prempro (premarin;cycrin)

Rating

74/100

New

Pharmacy pays

~$2.89 /30

—

Type

Active ingredient

PRIMIDONE

ESTROGENS, CONJUGATED AND MEDROXYPROGESTERONE ACETATE

Manufacturer

Valeant Pharm Intl

Wyeth Pharms Inc

Dosage forms

Tablet

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

What is the difference between Mysoline and Prempro (Premarin;Cycrin)?

Mysoline contains Primidone, while Prempro (Premarin;Cycrin) contains Estrogens, Conjugated and Medroxyprogesterone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.