MYSOLINE vs NEO-CORT-DOME

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. MYSOLINE and NEO-CORT-DOME are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MYSOLINE	NEO-CORT-DOME
Rating	74/100	New
Pharmacy pays	~$2.89 /30	$0.15 /g
Type	RX	RX
Active ingredient	PRIMIDONE	HYDROCORTISONE AND NEOMYCIN SULFATE
Manufacturer	Valeant Pharm Intl	Bayer Pharms
Dosage forms	Tablet	Topical, Drops
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Half-life	—	about 1.5 hours
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor	—

mysoline neo-cort-dome

Rating

74/100

New

Pharmacy pays

~$2.89 /30

$0.15 /g

Type

Active ingredient

PRIMIDONE

HYDROCORTISONE AND NEOMYCIN SULFATE

Manufacturer

Valeant Pharm Intl

Bayer Pharms

Dosage forms

Tablet

Topical, Drops

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Half-life

—

about 1.5 hours

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

—

Frequently asked questions

What is the difference between Mysoline and Neo-Cort-Dome?

Mysoline contains Primidone, while Neo-Cort-Dome contains Hydrocortisone and Neomycin Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.