MOTRIN MIGRAINE PAIN vs VOLTAREN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. MOTRIN MIGRAINE PAIN and VOLTAREN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MOTRIN MIGRAINE PAIN	VOLTAREN
Rating	70/100	70/100
Pharmacy pays	$0.04 /mL	$0.36 /mL
Type	RX	RX
Active ingredient	IBUPROFEN	DICLOFENAC SODIUM
Manufacturer	Kenvue Brands	Novartis
Dosage forms	Tablet	Tablet, delayed release
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 1.8 to 2.0 hours	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

motrin migraine pain voltaren

Rating

70/100

Pharmacy pays

$0.04 /mL

$0.36 /mL

Type

Active ingredient

IBUPROFEN

DICLOFENAC SODIUM

Manufacturer

Kenvue Brands

Novartis

Dosage forms

Tablet

Tablet, delayed release

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

Which is better-rated, Motrin Migraine Pain or Voltaren?

Motrin Migraine Pain and Voltaren are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Motrin Migraine Pain or Voltaren?

Motrin Migraine Pain costs pharmacies less to acquire — about $0.04 vs $0.36 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Motrin Migraine Pain and Voltaren?

Motrin Migraine Pain contains Ibuprofen, while Voltaren contains Diclofenac Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.