MOTRIN IB vs RUFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	MOTRIN IB	RUFEN
Rating	70/100	70/100
Pharmacy pays	$0.04 /mL	$0.04 /mL
Type	OTC	RX
Active ingredient	IBUPROFEN	IBUPROFEN
Manufacturer	Kenvue Brands	Basf
Dosage forms	Capsule, Tablet	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 1.8 to 2.0 hours	about 1.8 to 2.0 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

motrin ib rufen

Rating

70/100

Pharmacy pays

$0.04 /mL

Type

OTC

Active ingredient

IBUPROFEN

Manufacturer

Kenvue Brands

Basf

Dosage forms

Capsule, Tablet

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

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Where to buy

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Frequently asked questions

Which is better-rated, Motrin Ib or Rufen?

Motrin Ib and Rufen are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Motrin Ib or Rufen?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Motrin Ib and Rufen?

Both Motrin Ib and Rufen share the active ingredient Ibuprofen, but Motrin Ib is sold as OTC and Rufen as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.