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MORPHINE SULFATE vs ULTRAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. MORPHINE SULFATE and ULTRAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$2.61 /mL
~$0.72 /30

Type

RX
RX

Active ingredient

MORPHINE SULFATE
TRAMADOL HYDROCHLORIDE

Dosage forms

Tablet, Tablet, extended release
Tablet

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 2 hours
about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Dyspnea, Intractable Pain
Pain

Frequently asked questions

What is the difference between Morphine Sulfate and Ultram?

Morphine Sulfate contains Morphine Sulfate, while Ultram contains Tramadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.