MONOPRIL vs PRINIVIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. MONOPRIL and PRINIVIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MONOPRIL	PRINIVIL
Rating	72/100	70/100
Pharmacy pays	~$5.05 /30	~$0.77 /30
Type	RX	RX
Active ingredient	FOSINOPRIL SODIUM	LISINOPRIL
Manufacturer	Bristol Myers Squibb	Merck
Dosage forms	Tablet	Tablet
Drug class	Angiotensin Converting Enzyme Inhibitor	Angiotensin Converting Enzyme Inhibitor
Boxed warning	None	None
Half-life	—	about 12 hours (the effective half-life, in adults with normal kidney function)
Treats	Diabetic Nephropathies, Heart Failure, Hypertension	Diabetic Nephropathies, Heart Failure, Hypertension

monopril prinivil

Rating

72/100

70/100

Pharmacy pays

~$5.05 /30

~$0.77 /30

Type

Active ingredient

FOSINOPRIL SODIUM

LISINOPRIL

Manufacturer

Bristol Myers Squibb

Merck

Dosage forms

Tablet

Drug class

Angiotensin Converting Enzyme Inhibitor

Boxed warning

None

Half-life

—

about 12 hours (the effective half-life, in adults with normal kidney function)

Treats

Diabetic Nephropathies, Heart Failure, Hypertension

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Frequently asked questions

Which is better-rated, Monopril or Prinivil?

By our independent rating, Monopril scores higher — 3.6 vs 3.5 out of 5 for Prinivil. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Monopril or Prinivil?

Prinivil costs pharmacies less to acquire — about $0.77 vs $5.05 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Monopril and Prinivil?

Monopril contains Fosinopril Sodium, while Prinivil contains Lisinopril — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.