MONISTAT 5 vs SPORANOX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. MONISTAT 5 and SPORANOX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MONISTAT 5	SPORANOX
Rating	New	70/100
Pharmacy pays	—	$0.84 /mL
Type	RX	RX
Active ingredient	MICONAZOLE NITRATE	ITRACONAZOLE
Manufacturer	Personal Prods	Janssen Pharms
Dosage forms	Tampon	Capsule
Drug class	Azole Antifungal	Azole Antifungal
Boxed warning	None	None
Half-life	—	Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.
Treats	Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis	Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

monistat 5 sporanox

Rating

New

70/100

Pharmacy pays

—

$0.84 /mL

Type

Active ingredient

MICONAZOLE NITRATE

ITRACONAZOLE

Manufacturer

Personal Prods

Janssen Pharms

Dosage forms

Tampon

Capsule

Drug class

Azole Antifungal

Boxed warning

None

Half-life

—

Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis

Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

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Frequently asked questions

What is the difference between Monistat 5 and Sporanox?

Monistat 5 contains Miconazole Nitrate, while Sporanox contains Itraconazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.