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MIRAPEX vs REQUIP XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. MIRAPEX and REQUIP XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$2.01 /30
~$2.41 /30

Type

RX
RX

Active ingredient

PRAMIPEXOLE DIHYDROCHLORIDE
ROPINIROLE HYDROCHLORIDE

Dosage forms

Tablet
Tablet, extended release

Drug class

Nonergot Dopamine Agonist
Nonergot Dopamine Agonist

Boxed warning

None
None

Half-life

about 6 hours

Treats

Depressive Disorder, Parkinson Disease
Parkinson Disease

Get mirapexhigher-rated option

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Frequently asked questions

Which is better-rated, Mirapex or Requip XL?

By our independent rating, Mirapex scores higher — 3.6 vs 3.5 out of 5 for Requip XL. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Mirapex or Requip XL?

Mirapex costs pharmacies less to acquire — about $2.01 vs $2.41 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Mirapex and Requip XL?

Mirapex contains Pramipexole Dihydrochloride, while Requip XL contains Ropinirole Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.