MEXILETINE HYDROCHLORIDE vs SORINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. MEXILETINE HYDROCHLORIDE and SORINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MEXILETINE HYDROCHLORIDE	SORINE
Rating	70/100	New
Pharmacy pays	~$8.44 /30	~$2.96 /30
Type	RX	RX
Active ingredient	MEXILETINE HYDROCHLORIDE	SOTALOL HYDROCHLORIDE
Manufacturer	Macleods Pharms Ltd	Aiping Pharm Inc
Dosage forms	Capsule	Tablet
Drug class	Antiarrhythmic	Antiarrhythmic
Boxed warning	None	Boxed warning
Half-life	—	about 12 hours (the label gives a mean elimination half-life of 12 hours)
Treats	Diabetic Neuropathies, Ventricular Fibrillation, Ventricular Premature Complexes	Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia

mexiletine hydrochloride sorine

Rating

70/100

New

Pharmacy pays

~$8.44 /30

~$2.96 /30

Type

Active ingredient

MEXILETINE HYDROCHLORIDE

SOTALOL HYDROCHLORIDE

Manufacturer

Macleods Pharms Ltd

Aiping Pharm Inc

Dosage forms

Capsule

Tablet

Drug class

Antiarrhythmic

Boxed warning

None

Boxed warning

Half-life

—

about 12 hours (the label gives a mean elimination half-life of 12 hours)

Treats

Diabetic Neuropathies, Ventricular Fibrillation, Ventricular Premature Complexes

Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia

Frequently asked questions

Which is cheaper, Mexiletine Hydrochloride or Sorine?

Sorine costs pharmacies less to acquire — about $2.96 vs $8.44 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Mexiletine Hydrochloride and Sorine?

Mexiletine Hydrochloride contains Mexiletine Hydrochloride, while Sorine contains Sotalol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.