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METROGEL-VAGINAL vs PROTOSTAT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

$0.10 /g
$0.10 /g

Type

RX
RX

Active ingredient

METRONIDAZOLE
METRONIDAZOLE

Dosage forms

Topical
Tablet

Drug class

Nitroimidazole Antimicrobial
Nitroimidazole Antimicrobial

Boxed warning

None
None

Half-life

about 8 hours
about 8 hours

Treats

Abscess, Amebiasis, Bacteroides Infections
Abscess, Amebiasis, Bacteroides Infections

Frequently asked questions

Which is cheaper, Metrogel-Vaginal or Protostat?

Pharmacies pay about the same to acquire either one — roughly $0.10 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Metrogel-Vaginal and Protostat?

Both Metrogel-Vaginal and Protostat share the active ingredient Metronidazole.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.