METOPROLOL TARTRATE vs TOPROL-XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. METOPROLOL TARTRATE and TOPROL-XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METOPROLOL TARTRATE	TOPROL-XL
Rating	60/100	New
Pharmacy pays	~$0.58 /30	~$0.58 /30
Type	RX	RX
Active ingredient	METOPROLOL TARTRATE	METOPROLOL SUCCINATE
Manufacturer	Hospira	Melinta Therap
Dosage forms	Injectable, Solution, Tablet	Tablet, extended release
Drug class	Beta-Adrenergic Blocker	Beta-Adrenergic Blocker
Boxed warning	None	None
Half-life	about 3 to 4 hours	about 3 to 4 hours
Treats	Angina Pectoris, Atrial Fibrillation, Atrial Flutter	Angina Pectoris, Atrial Fibrillation, Atrial Flutter

metoprolol tartrate toprol-xl

Rating

60/100

New

Pharmacy pays

~$0.58 /30

Type

Active ingredient

METOPROLOL TARTRATE

METOPROLOL SUCCINATE

Manufacturer

Hospira

Melinta Therap

Dosage forms

Injectable, Solution, Tablet

Tablet, extended release

Drug class

Beta-Adrenergic Blocker

Boxed warning

None

Half-life

about 3 to 4 hours

Treats

Angina Pectoris, Atrial Fibrillation, Atrial Flutter

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Frequently asked questions

Which is cheaper, Metoprolol Tartrate or Toprol-XL?

Pharmacies pay about the same to acquire either one — roughly $0.58 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Metoprolol Tartrate and Toprol-XL?

Metoprolol Tartrate contains Metoprolol Tartrate, while Toprol-XL contains Metoprolol Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.