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METHYLDOPA vs NEXICLON XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. METHYLDOPA and NEXICLON XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

methyldopanexiclon xr

Rating

70/100
New

Pharmacy pays

~$225.00 /30
~$1.05 /30

Type

RX
RX

Active ingredient

METHYLDOPA
CLONIDINE

Manufacturer

Heritage Pharma
Rosemont

Dosage forms

Tablet
Tablet, extended release

Drug class

Central Alpha-2 Adrenergic Agonist
Central Alpha-2 Adrenergic Agonist

Boxed warning

None
None

Half-life

about 105 minutes (roughly 1.75 hours)
about 12 to 16 hours

Treats

Hypertension
Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

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Frequently asked questions

Which is cheaper, Methyldopa or Nexiclon XR?

Nexiclon XR costs pharmacies less to acquire — about $1.05 vs $225.00 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Methyldopa and Nexiclon XR?

Methyldopa contains Methyldopa, while Nexiclon XR contains Clonidine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.