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METHIMAZOLE vs TIROSINT-SOL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. METHIMAZOLE and TIROSINT-SOL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
66/100

Pharmacy pays

~$2.28 /30
~$1.83 /30

Type

RX
RX

Active ingredient

METHIMAZOLE
LEVOTHYROXINE SODIUM

Dosage forms

Tablet
Solution

Drug class

Thyroid Hormone Synthesis Inhibitor
L-Thyroxine

Boxed warning

Half-life

about 6 to 7 days in adults with normal thyroid function

Treats

Goiter, Thyroid Crisis
Goiter, Myxedema, Thyroid Neoplasms

Frequently asked questions

Which is cheaper, Methimazole or Tirosint-Sol?

Tirosint-Sol costs pharmacies less to acquire — about $1.83 vs $2.28 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Methimazole and Tirosint-Sol?

Methimazole contains Methimazole, while Tirosint-Sol contains Levothyroxine Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.