METHADOSE vs VANTRELA ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. METHADOSE and VANTRELA ER are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METHADOSE	VANTRELA ER
Rating	70/100	New
Pharmacy pays	$0.18 /mL	~$239.83 /30
Type	RX	RX
Active ingredient	METHADONE HYDROCHLORIDE	HYDROCODONE BITARTRATE
Manufacturer	Specgx LLC	Teva Branded Pharm
Dosage forms	—	Tablet, extended release
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	None
Half-life	about 8 to 59 hours (terminal/elimination half-life; a very wide range)	about 3.8 hours (3.8 ± 0.3 hours)
Treats	Opioid-Related Disorders, Intractable Pain	Cough, Obstructive Lung Diseases, Postoperative Pain

methadose vantrela er

Rating

70/100

New

Pharmacy pays

$0.18 /mL

~$239.83 /30

Type

Active ingredient

METHADONE HYDROCHLORIDE

HYDROCODONE BITARTRATE

Manufacturer

Specgx LLC

Teva Branded Pharm

Dosage forms

—

Tablet, extended release

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

about 3.8 hours (3.8 ± 0.3 hours)

Treats

Opioid-Related Disorders, Intractable Pain

Cough, Obstructive Lung Diseases, Postoperative Pain

Frequently asked questions

What is the difference between Methadose and Vantrela ER?

Methadose contains Methadone Hydrochloride, while Vantrela ER contains Hydrocodone Bitartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.