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METHADOSE vs ROXYBOND

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. METHADOSE and ROXYBOND are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

$0.18 /mL
$0.08 /mL

Type

RX
RX

Active ingredient

METHADONE HYDROCHLORIDE
OXYCODONE HYDROCHLORIDE

Dosage forms

Tablet

Drug class

Opioid Agonist
Opioid Agonist

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)
about 3.5 to 4 hours

Treats

Opioid-Related Disorders, Intractable Pain
Postoperative Pain

Frequently asked questions

Which is cheaper, Methadose or Roxybond?

Roxybond costs pharmacies less to acquire — about $0.08 vs $0.18 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Methadose and Roxybond?

Methadose contains Methadone Hydrochloride, while Roxybond contains Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.