METHADOSE vs QDOLO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. METHADOSE and QDOLO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METHADOSE	QDOLO
Rating	70/100	New
Pharmacy pays	$0.18 /mL	~$0.72 /30
Type	RX	RX
Active ingredient	METHADONE HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE
Manufacturer	Specgx LLC	Rosemont
Dosage forms	—	Solution
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	Boxed warning
Half-life	about 8 to 59 hours (terminal/elimination half-life; a very wide range)	about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)
Treats	Opioid-Related Disorders, Intractable Pain	Pain

methadose qdolo

Rating

70/100

New

Pharmacy pays

$0.18 /mL

~$0.72 /30

Type

Active ingredient

METHADONE HYDROCHLORIDE

TRAMADOL HYDROCHLORIDE

Manufacturer

Specgx LLC

Rosemont

Dosage forms

—

Solution

Drug class

Opioid Agonist

Boxed warning

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Opioid-Related Disorders, Intractable Pain

Pain

Frequently asked questions

What is the difference between Methadose and Qdolo?

Methadose contains Methadone Hydrochloride, while Qdolo contains Tramadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.