METHADONE HYDROCHLORIDE vs METHADOSE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Attribute	METHADONE HYDROCHLORIDE	METHADOSE
Rating	72/100	70/100
Pharmacy pays	$0.18 /mL	$0.18 /mL
Type	RX	RX
Active ingredient	METHADONE HYDROCHLORIDE	METHADONE HYDROCHLORIDE
Manufacturer	Hikma	Specgx LLC
Dosage forms	Injectable, Solution, Tablet	—
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	Boxed warning
Half-life	about 8 to 59 hours (terminal/elimination half-life; a very wide range)	about 8 to 59 hours (terminal/elimination half-life; a very wide range)
Treats	Opioid-Related Disorders, Intractable Pain	Opioid-Related Disorders, Intractable Pain

methadone hydrochloride methadose

Rating

72/100

70/100

Pharmacy pays

$0.18 /mL

Type

Active ingredient

METHADONE HYDROCHLORIDE

Manufacturer

Hikma

Specgx LLC

Dosage forms

Injectable, Solution, Tablet

—

Drug class

Opioid Agonist

Boxed warning

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is better-rated, Methadone Hydrochloride or Methadose?

By our independent rating, Methadone Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Methadose. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Methadone Hydrochloride or Methadose?

Pharmacies pay about the same to acquire either one — roughly $0.18 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Methadone Hydrochloride and Methadose?

Both Methadone Hydrochloride and Methadose share the active ingredient Methadone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.