METHADONE HYDROCHLORIDE vs ULTIVA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. METHADONE HYDROCHLORIDE and ULTIVA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METHADONE HYDROCHLORIDE	ULTIVA
Rating	72/100	70/100
Pharmacy pays	$0.18 /mL	—
Type	RX	RX
Active ingredient	METHADONE HYDROCHLORIDE	REMIFENTANIL HYDROCHLORIDE
Manufacturer	Hikma	Mylan Institutional
Dosage forms	Injectable, Solution, Tablet	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	Boxed warning
Half-life	about 8 to 59 hours (terminal/elimination half-life; a very wide range)	—
Treats	Opioid-Related Disorders, Intractable Pain	Pain

methadone hydrochloride ultiva

Rating

72/100

70/100

Pharmacy pays

$0.18 /mL

—

Type

Active ingredient

METHADONE HYDROCHLORIDE

REMIFENTANIL HYDROCHLORIDE

Manufacturer

Hikma

Mylan Institutional

Dosage forms

Injectable, Solution, Tablet

Injectable

Drug class

Opioid Agonist

Boxed warning

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

—

Treats

Opioid-Related Disorders, Intractable Pain

Pain

Frequently asked questions

Which is better-rated, Methadone Hydrochloride or Ultiva?

By our independent rating, Methadone Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Ultiva. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Methadone Hydrochloride and Ultiva?

Methadone Hydrochloride contains Methadone Hydrochloride, while Ultiva contains Remifentanil Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.